Methotrexate safe and effective for ankylosing spondylitis

Methotrexate therapy is safe and effective for patients with ankylosing spondylitis, according to a recent six-month study in the Journal of Rheumatology.To evaluate the efficacy and safety of methotrexate (MTX), compared with placebo, in patients with active ankylosing spondylitis (AS), the research team, led by Dr Gonzalez-Lopez, allocated subjects to receive MTX 7.5 mg/week or placebo. They determined outcomes using a composite index of improvement of at least 20% in five of the following areas:...